$ads={1}
(Senior) Associate Scientist CMC Analytics
- Location: Ghent, BE
- This is a Lab based role with possibility of working 2 days/month from home
- Job type: Permanent, full time
About the job
Join Sanofi within our R&D site in Ghent as (Senior) Associate Scientist - CMC Analytics – BioPhysical Profiling team.
In this role you will be responsible of designing and conducting studies in the field of biophysical characterization, developability and early formulation development of NANOBODY® molecules but also of innovative and challenging new modalities. You will be involved in several projects with focus on protein analytics or CMC (either projects in pre-clinical stage and/or platform improvement projects) in collaboration with the entire analytical team and other departments where applicable.
About our team
At Sanofi Ghent, we discover and develop NANOBODY® molecules, a novel class of therapeutic proteins based on single domain antibody fragments derived from Camelids or Llamas. NANOBODY® molecules make a significant difference in the treatment of serious human diseases. No wonder our people are so motivated to give their best.
Each day you get a chance to contribute, to develop your skills and experience but also to be part of a young, fast moving, and international company.
The BioPhysical Profiling team, part of the Analytics group of the CMC Pharmaceutical Development & Technology Department is responsible for non-GMP R&D activities to support Nanobody discovery, developability and (pre)-clinical development activities up to FIH.
Main responsibilities
- Implement new technologies and / or predictive assays to strengthen our NANOBODY® development workflow
- Report your data in electronic lab notebooks and databases to prepare for statistical or other big data analysis
- Perform biophysical analysis (SE-UHPLC, DLS, HIC) to support the NANOBODY® lead optimization
- Perform pre-formulation studies to support the NANOBODY® lead selection (Buffer preparation, A2/KD, Tagg)
- Perform stability studies using a plethora of different techniques including e.g. chromatography, charge variants and subvisible particle analysis.
- Prepare experimental plan and plan lab activities independently, training/coaching of junior associate scientist
- Be involved in data analysis and prepare summary presentation or reports of your results
- Communicate results and observations to the team
- Actively contribute to project-oriented teams and to lab organization routine tasks
About you
- Degree of Bachelor (5+ years of experience is an asset)/Master (3+ years of experience is an asset) in Biotechnology/Biomedical sciences or equivalent, job level depending on years of experience
- Experience in a relevant field: Biophysical and chemical analysis or biologics, liquid or lyophylized protein formulation
- Experience in any field or assay mentioned above is a plus
- Experience in statistical analysis, digitalization or big data analysis is a plus
- A pro-active approach and high sense for quality, accuracy, and detail
- A team-oriented attitude, flexibility, enthusiasm, and ability to design experiments independently, to plan and perform experiments and to prepare concise reports of the results
- Excellent communication skills and sense for initiative, creativity, and flexibility
- Oral and written fluency in English
The motivation letter and the CV of the applicant should be in English, and include a paragraph specifying the relevant technical expertise.
Pursue progress, discover extraordinary.
Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.
At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.
Watch our
ALL IN video
and check out our Diversity Equity and Inclusion actions at sanofi.com
!
#LI-EUR
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
$ads={2}
